Customer benefits

Efficient project management

Complex packaging formats

New levels of productivity

Rapid format changeovers

Achieved new target of 1,200 antacid preparation sticks per minute

Designed with high visibility for ease of use

Certified to IQ-OQ standard

Local regulatory compliance in 23 countries

Compact design in limited floorspace

“Mpac was the best company for the project, both in terms of product quality and levels of knowledge. Since installation, the machine has proved to be robust and extremely reliable; delivering the right results without disruption.”
Head of Engineering and Maintenance Production, Nattermann Pharmaceuticals

Customer

Nattermann Pharmaceuticals (part of the global Sanofi Group).

Challenge

To support the manufacturer’s move to a new, convenient stick pack format for its liquid antacid preparation.

The need for a highly flexible approach to accommodate an active export business – currently 23 target markets and growing – made this an exceptionally complex task.

Dose volumes varied according to local regulations, which meant that stick size did too; four different variables were required, with 140mm and 160mm the most common. The number of sticks in each pack was also subject to change; ten options were identified, ranging from six to 50 sticks per pack.

In addition, Nattermann Pharmaceuticals had set an ambitious packaging target of 1,200 sticks per minute – despite initially not being sure if any machine was capable of reaching this level of speed. It was only after detailed research into potential partners that the company awarded the contract to Mpac.

Solution

The built-in agility of Mpac’s packaging machinery, together with the ingenuity of our engineers, inspired the development of a solution custom-built to meet the company’s ambitious brief.

Mpac’s machine was integrated into the new manufacturing line, where it handled two separate product streams and hit the exceptionally-high packaging target of 1,200 sticks per minute; successfully pushing the boundaries in terms of achievable speed.

The frequent format changes were carried out within defined timeframes. Plus, the inclusion of an essential product information leaflet in each pack was also factored into the overall system, without any negative impact on overall speed.

Detailed acceptance tests before the packaging process addressed the fundamental need for compliance with stringent pharmaceutical regulations. Certification demonstrated the system had achieved the correct regulatory standards and, in particular, the Installation Qualification, Operation Qualification (IQ-OQ).

Given the limited designated space for the pharma packaging machine, a range of tests were also carried out as part of the pre-contract phase to validate the practical limitations of the design in these circumstances. This was just one example of how Mpac’s detailed project management approach and proven engineering expertise were instrumental to the successful outcome.

Interested in understanding how we tackle complex challenges like these?

Call us on: +44(0)24 7642 1100